Can yoyo loaches live with otocinclus?

Verdict
Yes

Yes, yoyo loaches and otocinclus can live together. Both are fine at 75–79°F. Plan on at least 40 gal.

Yoyo loachYoyo loach75–86°F · pH 6–7.5 OtocinclusOtocinclus72–79°F · pH 6–7.5

Why it works

Water side by side

55°60°65°70°75°80°85°90°Both: 75–79°Yoyo loach 75–86°Otocinclus 72–79°
The green band is the temperature range both can live in.
456789Both: 6–7.5Yoyo loach 6–7.5Otocinclus 6–7.5
The green band is the pH both tolerate.

Size to scale

Yoyo loach · 5 inOtocinclus · 2 in0"1"2"3"4"5"6"
Adult length in an aquarium. A fish can swallow anything that fits in its mouth, roughly a third to half its own length for predators.

Care at a glance

Yoyo loachOtocinclus
Temperature75–86 °F72–79 °F
pH6–7.56–7.5
Adult size5.0 in2.0 in
Minimum tank40 gal20 gal
TemperamentSemi-aggressivePeaceful
Swims atBottomBottom
GroupGroups of 5+Groups of 6+
DietOmnivoreHerbivore

Better tank mates for yoyo loaches

All yoyo loach tank mates

Better tank mates for otocinclus

All otocinclus tank mates

Questions

Can yoyo loaches live with otocinclus?

Yes, yoyo loaches and otocinclus can live together. Both are fine at 75–79°F. Plan on at least 40 gal.

What temperature suits both yoyo loaches and otocinclus?

75–79 °F. Yoyo loaches need 75–86 °F, otocinclus need 72–79 °F.

What size tank do yoyo loaches and otocinclus need together?

At least 40 gal, set by the yoyo loach. Add space for each extra fish.