Can guppies live with zebra plecos?

Verdict
Yes

Yes. Guppies and zebra plecos make a good pair. Both are fine at 79–82°F. Plan on at least 30 gal.

GuppyGuppy72–82°F · pH 6.8–7.8 Zebra plecoZebra pleco79–88°F · pH 6–7.5

Why it works

Water side by side

55°60°65°70°75°80°85°90°Both: 79–82°Guppy 72–82°Zebra pleco 79–88°
The green band is the temperature range both can live in.
456789Both: 6.8–7.5Guppy 6.8–7.8Zebra pleco 6–7.5
The green band is the pH both tolerate.

Size to scale

Guppy · 2 inZebra pleco · 3.5 in0"1"2"3"4"5"6"
Adult length in an aquarium. A fish can swallow anything that fits in its mouth, roughly a third to half its own length for predators.

Care at a glance

GuppyZebra pleco
Temperature72–82 °F79–88 °F
pH6.8–7.86–7.5
Adult size2.0 in3.5 in
Minimum tank10 gal30 gal
TemperamentPeacefulPeaceful
Swims atTopBottom
GroupGroups of 3+Alone or in pairs
DietOmnivoreCarnivore

Better tank mates for guppies

All guppy tank mates

Better tank mates for zebra plecos

All zebra pleco tank mates

Questions

Can guppies live with zebra plecos?

Yes. Guppies and zebra plecos make a good pair. Both are fine at 79–82°F. Plan on at least 30 gal.

What temperature suits both guppies and zebra plecos?

79–82 °F. Guppies need 72–82 °F, zebra plecos need 79–88 °F.

What size tank do guppies and zebra plecos need together?

At least 30 gal, set by the zebra pleco. Add space for each extra fish.