Can bristlenose plecos live with yoyo loaches?

Verdict
Yes

Yes. Bristlenose plecos and yoyo loaches get along in the same tank. Both are fine at 75–81°F. Plan on at least 40 gal.

Why it works

Water side by side

55°60°65°70°75°80°85°90°Both: 75–81°Bristlenose pleco 73–81°Yoyo loach 75–86°
The green band is the temperature range both can live in.
456789Both: 6.5–7.5Bristlenose pleco 6.5–7.5Yoyo loach 6–7.5
The green band is the pH both tolerate.

Size to scale

Bristlenose pleco · 5 inYoyo loach · 5 in0"1"2"3"4"5"6"
Adult length in an aquarium. A fish can swallow anything that fits in its mouth, roughly a third to half its own length for predators.

Care at a glance

Bristlenose plecoYoyo loach
Temperature73–81 °F75–86 °F
pH6.5–7.56–7.5
Adult size5.0 in5.0 in
Minimum tank30 gal40 gal
TemperamentPeacefulSemi-aggressive
Swims atBottomBottom
GroupAlone or in pairsGroups of 5+
DietHerbivoreOmnivore

Better tank mates for bristlenose plecos

All bristlenose pleco tank mates

Better tank mates for yoyo loaches

All yoyo loach tank mates

Questions

Can bristlenose plecos live with yoyo loaches?

Yes. Bristlenose plecos and yoyo loaches get along in the same tank. Both are fine at 75–81°F. Plan on at least 40 gal.

What temperature suits both bristlenose plecos and yoyo loaches?

75–81 °F. Bristlenose plecos need 73–81 °F, yoyo loaches need 75–86 °F.

What size tank do bristlenose plecos and yoyo loaches need together?

At least 40 gal, set by the yoyo loach. Add space for each extra fish.