Can axolotls live with otocinclus?

Verdict
No

No. Axolotls and otocinclus should not share a tank. Axolotls are coldwater animals (60–66°F); otocinclus need 72–79°F. No temperature suits both.

What to watch

What works

Water side by side

55°60°65°70°75°80°85°90°Axolotl 60–66°Otocinclus 72–79°
The ranges do not meet, so one of them would always be too warm or too cold.
456789Both: 6.5–7.5Axolotl 6.5–8Otocinclus 6–7.5
The green band is the pH both tolerate.

Size to scale

Axolotl · 10 inOtocinclus · 2 in0"2"4"6"8"10"
Adult length in an aquarium. A fish can swallow anything that fits in its mouth, roughly a third to half its own length for predators.

Care at a glance

AxolotlOtocinclus
Temperature60–66 °F72–79 °F
pH6.5–86–7.5
Adult size10.0 in2.0 in
Minimum tank20 gal20 gal
TemperamentPeacefulPeaceful
Swims atBottomBottom
GroupAlone or in pairsGroups of 6+
DietCarnivoreHerbivore

Better tank mates for otocinclus

All otocinclus tank mates

Questions

Can axolotls live with otocinclus?

No. Axolotls and otocinclus should not share a tank. Axolotls are coldwater animals (60–66°F); otocinclus need 72–79°F. No temperature suits both.

What temperature suits both axolotls and otocinclus?

None. Axolotls need 60–66 °F and otocinclus need 72–79 °F, so the ranges do not meet.

What size tank do axolotls and otocinclus need together?

At least 20 gal, set by the axolotl. Add space for each extra fish.